HRT.so
Gender-Affirming Hormone Therapy
4.8 Rating
Intramuscular or subcutaneous injection (weekly)

Masculinizing Testosterone Therapy

Testosterone therapy for masculinizing effects, used by transgender men and non-binary individuals seeking virilization.

Overview

Masculinizing testosterone therapy uses testosterone (cypionate or enanthate) to induce virilizing physical changes. This therapy promotes voice deepening, facial hair growth, muscle development, fat redistribution, and cessation of menstruation. It is a cornerstone of gender-affirming care for transmasculine individuals.

How It Works

Exogenous testosterone binds to androgen receptors, triggering masculinizing gene expression. This leads to increased muscle protein synthesis, stimulation of hair follicles for facial/body hair growth, laryngeal changes for voice deepening, and suppression of the menstrual cycle.

Benefits

Voice deepening
Facial and body hair growth
Increased muscle mass
Fat redistribution
Cessation of menstruation
Masculine body composition

Potential Side Effects

Acne
Hair loss (MPB pattern)
Mood changes
Vaginal atrophy
Elevated hematocrit
Weight gain

Dosage Information

Typical starting dose is 50-100mg testosterone cypionate or enanthate weekly via intramuscular or subcutaneous injection. Dosing is adjusted to maintain testosterone levels in the male reference range.

Quick Facts

Administration

Intramuscular or subcutaneous injection (weekly)

Rating

4.8 / 5.0

Category

Gender-Affirming Hormone Therapy

Common Symptoms

Gender dysphoria
Desire for voice deepening
Need for facial hair growth
Seeking masculine body composition

Common Questions

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